Dr. Perlmutter discusses new science regarding low-carb, high-fat diets (ketogenic), gut bacterial diversity and exercise for optimal brain health.
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02:07 Confusion Over Carbohydrates:
03:44 The Real Problem with Carbs:
05:29 Eating for Your Microbiome
07:44 Why Fat is Blamed
09:00 Gut Bacteria Diversity and FMT
FMT (Fecal Microbial Transplant) has been published in medical literature for 50 years or more. Delivering probiotics or fully formed microbiota via the rectal route offers huge potential. Today, more than 500 hospitals in America perform FMT for the treatment of C. diff. C. diff can be contracted via the use of acid blocking drugs or the use of antibiotics, both of which disrupt the complexity and diversity of your gut microbiome. The success rate of FMT for C. diff is 94 to 96%. The approved standard treatment with antibiotics is about 26 to 28% effective.
10:07 C-Sections: Maria Dominguez-Bello at NYU Medical School has published a series of papers. The most recent of which in the journal Nature, where she has advocated putting a swab in the vaginal birth canal prior to a C-section and mandatory intravenous antibiotics, keeping the swab in a warm moist environment. After the baby is born, inoculate baby’s face and mouth with the contents of the birth canal. These are the seeds for the microbiome.
13:30 Problems with High Fat in the Research:
16:18 Oral Microbiome: Studies of the oral microbiome of our ancestors found two dramatic times when there were changes: 10,000 years ago and 200 years ago. These correlate with the development of agriculture and the development of processed sugar. The reduction of diversity in our microbiome is passed down to the next generation.
21:46 Gut Bacteria and Heart Disease
26:53 Ketogenic Diet, Cancer and Brain Health
31:25 Ways to Boost BDNF
36:40 Stop and Connection
38:21 Dr. Perlmutter’s Morning Routine
40:48 Dr. Perlmutter’s Favorite Nutrient
41:33 Dr. Perlmutter’s Number #1 Health Tip